Oxysterols in Autoimmunity
نویسندگان
چکیده
منابع مشابه
Macrophages, oxysterols and atherosclerosis.
Macrophages play central roles in immunity and homeostasis, and contribute to the pathogenesis of atherosclerosis through their accumulation of cholesterol and the production of inflammatory mediators and cytokines. Recent studies indicate that oxysterols influence diverse aspects of macrophage biology. Rather than simply being intermediates of cholesterol catabolism, oxysterols are also potent...
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The present research consisted of producing 3 types of powdered concentrates: the dairy, the egg and the dairy-egg (produced from a blend of raw liquid milk and liquid eggs). The dairy-egg powder was produced in order to facilitate formulation of dry food mixes. Powders were vacuumpackaged and packaged in air atmosphere and stored for 24 months. Changes in contents of selected oxysterols (deter...
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The ageing endothelium progressively loses its remarkable and crucial ability to maintain homeostasis of the vasculature, as it acquires a proinflammatory phenotype. Cellular and structural changes gradually accumulate in the blood vessels, and markedly in artery walls. Most changes in aged arteries are comparable to those occurring during the atherogenic process, the latter being more marked: ...
متن کاملOxysterols: Players in different metabolic leagues.
Thursday September 24th, 2015 8:30 9:00 Registration at the Venue (Gartensaal) 9:00 9:10 Opening of the Symposium: Dieter Lütjohann, Luigi Iuliano, Gérard Lizard 9:10 9:30 Welcome (Lecture Hall): Nicolas Wernert, Dean of the Medical Faculty, University of Bonn Gunther Hartmann, Chair, Institute of Clinical Chemistry and Clinical Pharmacology with the Central Laboratory of the University Hospita...
متن کاملOxysterols and Their Cellular Effectors
Oxysterols are oxidized 27-carbon cholesterol derivatives or by-products of cholesterol biosynthesis, with a spectrum of biologic activities. Several oxysterols have cytotoxic and pro-apoptotic activities, the ability to interfere with the lateral domain organization, and packing of membrane lipids. These properties may account for their suggested roles in the pathology of diseases such as athe...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2019
ISSN: 1422-0067
DOI: 10.3390/ijms20184522